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While the enhanced permeability and retention (EPR) effect is commonly leveraged for tumor targeting, its variability in human tumors, unlike in consistent preclinical mouse models, poses a challenge for reliable drug delivery to cancerous tissues

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Olfactory bulb targeted QD bioconjugate and Kv1.3 blocking peptide improve metabolic health in obese male mice

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It upregulates repair mechanisms while suppressing inflammatory and cancer-promoting pathways