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4.5 Targeting mitochondrial function and intercellular ferroptosis propagation in Alzheimers disease Mitochondria serve as a central hub for cellular energy metabolism and lipid peroxidation, playing a pivotal role in the amplification and integration of ferroptosis-related signals

The inhibition of glutathione peroxidase 4 (GPX4) or the depletion of glutathione (GSH) leads to ferroptosis by excessive lipid peroxidation and elevated intracellular lipid ROS

Because every persons body reacts differently, dosing must be personalized

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BRCA2 and TP53 mutations in a breast cancer patient: a case report and review of the literature