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Striatal and cortical neuron mitochondria display a loss of balance between fusion and fission [143, 144], and striatal neurons in asymptomatic mutation carriers show decreased expression of the key mitogenesis regulator PGC-1 [145]

Despite the numerous clinical trials that investigated the effect of enteral and parenteral glutamine supplementation in multiple trauma patients, the results are inconclusive

GSH is synthesised de novo from glutamate, cysteine and glycine [13] with a -carboxyl linkage between glutamate and cysteine of GSH, which is only susceptible to hydrolysis by glutamyltranspeptidase, [14] rather than the usual -carboxyl group

3,000 mcg B12 (methylcobalamin)

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