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The GLP-1RAs are resistant to DPP-4 degradation, have longer half-lives, and have been developed for the treatment of patients with type 2 diabetes mellitus (T2DM) [15]

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Preclinical studies demonstrated that sildenafil attenuated cardiomyocyte apoptosis, improved left ventricular function, and increased survival in doxorubicin-treated mice [184]

Disease modification in Parkinsons disease: current approaches, challenges, and future considerations