The diagnosis of MASLD is based on the confirmed presence of hepatic steatosis, determined by imaging techniques or biopsy, in combination with cardiometabolic risk factors such as obesity (i.e., elevated body mass index BMI), hypertension, IR, or dyslipidemia, while excluding significant alcohol consumption [18]
The LEADER trial showed that liraglutide reduced the risk of major cardiovascular events in people with type 2 diabetes.[4] Soon after, SUSTAIN-6 demonstrated similar benefits with semaglutide.[5] Then came REWIND, which suggested that cardiovascular protection could extend even to patients without established cardiovascular disease.[6] The SELECT trial made headlines because it showed cardiovascular benefits in people with overweight or obesity who did not have diabetes, a finding that challenged long-held assumptions about who might benefit from these medicines.[7] Most recently, an international trial called SOUL, which tested an oral form of semaglutide, included 788 Indian patients across 32 centres
What type of exercise best preserves muscle on semaglutide
Edition: November 2013
For chronic weight management, Wegovy is commonly prescribed at a recommended dosage of 2.4 mg once a week
