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Cellular mechanisms of thyroid hormones and interaction with nuclear receptors Thyroxine (T4) and triiodothyronine (T3) play crucial roles in metabolic processes regulation, growth, and development

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Human clinical and epidemiological evidence While numerous mechanistic studies have clarified the molecular pathways linking diabetes to impaired spermatogenesis, growing clinical and epidemiological evidence also supports this association in human populations

The proteolytic regulation of A39 is specific to the mitochondrial m -AAA protease AFG3L2, and cannot be substituted by other mitochondrial proteases that also act around the inner mitochondrial membrane 40,41