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32,33 Excess and unregulated nitric oxide production injures cell proteins and alters their functions

Weight gain and insulin resistance worsen mechanical stress, systemic inflammation, and the hormonal milieu that contributes to disease progression

While the science is still catching up, Byrne suspects that middle-aged women may be particularly vulnerable to "Ozempic face" because of hormonal shifts and a natural decline in collagen production during the menopause transition

Instead, it performs a more nuanced role, optimising the muscular environment so that the structural elements of a non surgical facelift (fillers, biostimulators, RF microneedling, lasers) can achieve their full potential

Fit but insulin-resistant Chronically inflamed Prone to sugar cravings Brain fog or burnout Family history of heart disease, diabetes, or dementia You dont need to be sick to optimize