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CT-388, a biased GLP-1R/GIPR co-agonist, produces rapid weight loss in obese humans: Phase 1 results

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A typical 400-l standard aldehyde formation assay was performed in 20 mM HEPES-NaOH pH 7.5, 10 mM MgCl 2 , 150 mM NaCl containing 5 M purified CntA, 15 M purified CntB, and 2 mM L-carnitine at 27C