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Emerging evidence suggests that a disturbed gut microbiota is an essential pathogenic mechanism in SLE development (106, 107)

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The lysed cells were then mixed with 1 mL of saline (0.85% NaCl, pH 6.0) and centrifuged at 10,000 g for 10 min at 4 C 28

Furthermore, alanine mutations of the established glutathione-scaffold site residue D90 or of crucial residue K26 in monothiol PfGrx C32S/C88S slowed down the reaction and resulted in linear secondary diagrams for the first rate constant (Fig