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I created this podcast because the volume of valuable discussion happening in patient forums is enormous, and I needed an easier way to consume it and stay across what patients are actually experiencing

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The field should adopt more rigorous standards, including the use of selective inhibitors and genetic tools to validate proposed hubs, and employ advanced ex vivo models like patient-derived cells or organoids to better assess the therapeutic relevance of these dual-targeting approaches before considering clinical translation

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Findings from preclinical and postmortem studies highlighted that brain insulin signaling is dysregulated in AD mouse and human brains (Griffith et al