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Contreras CM, Cooper IS, Fernandez-Guardiola A

This varied ontogeny is reflected in distinct mutational profiles 7 , histological features and molecular phenotypes, resulting in complex classification schemes aimed at different clinical objectives 8

Its primary mechanism of action is the upregulation of brain-derived neurotrophic factor (BDNF), a protein that supports neuronal survival, synaptic plasticity, and the formation of new neural connections

The bioavailability of LA is approximately 30% (2038%), primarily due to the first-pass effect in the liver [18]

It should be noted that this is a systemic treatment, meaning the effects are felt all over the body, not just on the face