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(2021) Efficacy and safety of dulaglutide 3.0 mg and 4.5 mg versus dulaglutide 1.5 mg in metformin-treated patients with type 2 Diabetes in a randomized controlled trial (AWARD-11) Using fat-dissolving injections that are not FDA approved can be harmful (2023) Sareen S

When combined with the reduced meat and dairy intake often seen with GLP-1 therapy, deficiency risk increases further

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Many peptides lack bioavailability and must be administered subcutaneously