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Under oxidative stress, NRF2 escapes KEAP1-mediated degradation [56], translocates to the nucleus, and activates antioxidant genes including HO-1 and NQO1

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Additionally, advancements in research have enabled the use of GLP-1 receptor agonists for obesity treatment, which is anticipated to expand their usage beyond diabetes management

However, weight rebounded significantly after stopping the drug

It binds to these toxins and facilitates their transport through bile or urine for excretion