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(PubMed) Volak LP, Ghirmai S, Cashman JR, Court MH

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The antioxidant system reduces the level of oxidative stress, stabilizes the KEAP1/NRF2 system, and inhibits the occurrence of oxeiptosis by clearing O 2 and HO [243]

Because cardiomyocytes are terminal differentiated cells, their loss in heart failure is irreversible, therefore, preventing cardiomyocyte hypertrophy and death is of great physiological significance for maintaining heart function and delaying heart failure