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Hydrogen peroxide must then be cleared by catalase, glutathione peroxidase and related antioxidant systems

In addition, overexpression of lipoprotein lipase (LPL) in liver or muscle induced peripheral insulin resistance and the accumulation of lipid in respective tissues [87,88], and skeletal muscle-specific LPL deletion enhanced insulin signaling in HFD challenged muscle [89]

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Now roughly 1 in 8 people in the United States are taking GLP-1s to lose weight, according to a tracking poll KFF conducted last year