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For these experiments, cells were seeded at the same density (12,992 cells per cm 2 ) in both the bottom well and the insert
Patient-reported outcome results in patients with type 2 diabetes treated with once-weekly dulaglutide: data from the AWARD phase III clinical trial programme
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FFA2 is activated predominantly by propionate and FFA3 by butyrate [EC 50 for acetate, propionate and butyrate at FFA2 are 431, 290 and 371 M respectively, and at FFA3 393, 41 and 33 M ( The gut microbiome is altered in obesity and T2D, an effect known as dysbiosis, where the ratio of the main bacterial phyla ( Firmicutes and Bacteroidetes ) becomes imbalanced, reducing diversity while the relative abundance of certain bacteria, including opportunistic pathogens, increases (Larsen et al., 2010)
J., Chory, J
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