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For example, improved insulin sensitivity can lower the chance of developing type 2 diabetes, a condition that can disrupt athletic performance and health over time

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So is considered well-tolerated and safe

In addition, with aging, the production and release of renin is reduced, so the total aldosterone level is also reduced, and the renin-angiotensin system (RAS) within the kidney and throughout the body is suppressed (Karam and Tuazon, 2013)