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Future randomized controlled IF trials should use biomarkers of the metabolic switch (e.g., plasma ketone levels) as a measure of compliance and the magnitude of negative energy balance during the fasting period

The iron in this product (18mg ferrous bisglycinate) is the full adult DV combining it with another iron source could exceed recommended intake levels

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National Institute for Health and Care Excellence (NICE) criteria for initiation of GLP-1 and GIP analogues is as follows: if triple therapy with metformin and two other oral drugs is not effective, not tolerated or contraindicated, consider triple therapy by switching one drug for a GLP-1 analogues for adults with T2DM who have a body mass index (BMI) of 35kg/m 2 or higher[15]

Q., Chan, K