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It should be noted that aerobic energy production is not the only function of the mitochondria

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While renal dysfunction progresses, the most important indicators of oxidative stress are plasma F2-isoprostanes, 8-oxo-7,8-dihydro-2-deoxyguanosine, malondialdehyde (MDA), carbamylated proteins, advanced oxidation protein products, asymmetric dimethylarginine, and oxidized lipoprotein particles (138, 141, 142)

It's like, okay, now you were on the drug and suddenly you're like, maybe this is what a lot of other people who haven't struggled with their weight feel like