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Provides foundational knowledge but is primarily didactic and less practice-focused

Once activated, they express -smooth muscle actin (-SMA) and synthesize collagen, as well as other extracellular matrix proteins, such as fibronectin [11]

The primary active ingredient is the same

Such scenarios necessitate a thorough evaluation of the potential benefits and risks, ensuring that patient safety remains the highest priority

Similarly, oxidative stress states such as sepsis and critical illness can predispose to pyroglutamate accumulation due to increased GSH demand driven by elevated reactive oxygen species production [65]