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PARP1 inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD(+) levels and increasing SIRT1 activity

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The single mutants GSAAT(C168S), GSAAT(C190S) and the double mutant GSAAT(C168S/C190S) all showed decreased redox-induced dimerization, suggesting a potential formation of an intramolcular disulfide bridge

NIR-I and NIR-II fluorescence images of the same mouse with an orthotopic liver tumor at 0, 30, and 70 min with intravenous injection of BH-NO2@BSA