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Nature 576 , 301305 (2019)

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In recent years, GLP-1 weight loss injections have emerged as a significant advancement in the treatment of obesity and related metabolic conditions

Primary outcome: Results Semaglutide showed robust therapeutic effects in treatment-seeking participants with obesity and alcohol use disorder and this trial supports previous preclinical and clinical findings suggesting GLP-1 receptor agonists as a potential novel treatment target for alcohol use disorder

Since semaglutide is more potent than liraglutide, many patients who achieved suboptimal results with Saxenda see additional weight loss when switching to semaglutide