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However, despite the financial windfall, both Lilly and Novo are also dealing with lingering, severe shortages related to fulfilling orders of their GLP-1 products

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In a separate study , published in JAMA in August 2025, the same researchers found that, across ages, GLP-1s were associated with lower risk of some obesity-related cancers, such as endometrial, ovarian, and meningioma cancers, but with an increased risk of kidney cancer, and nonsignificant changes for several other cancers

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They had very similar findings, where they saw that about 80% of their patients were taking [GLP-1s] for diabetes indications, and the weight loss ranged in the 2% to 3% range, [which] is even more modest than what we would expect