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In effect, thioctic acid acts as an amplifier, making the glutathione work harder and last longer than it would on its own

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Notably, symptom improvements in prebiotic-treated males persisted at weeks 2 and 12, contrasting with transient effects in placebo-treated males (Voigt et al., 2025)

The expression of liver de novo lipogenesis enzymes, ATP-citrate lyase (ACLY) and stearoyl-CoA desaturase 1 (SCD1), were suppressed with HF-SAAR feeding in both genotypes (Fig