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Am J Clin Nutr 62 : 802808

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doi: 10.1016/s0014-2999(96)00795-9

It became the first and unique trial to investigate the effect of dietary macronutrients on glycemic control in the context of intensive drug therapy (ClinicalTrial.gov, number ChiCTR-TRC-08000231) ( Materials and Methods Study Design The study design, preliminary results, and the full study protocol of the MARCH trial were previously published ( Participants Patients would be eligible for this study if they fulfilled the following criteria: (1) diagnosed with T2DM within the past 12 months according to 1999 WHO criteria, (2) without oral antidiabetic agents or short-term (i.e., 1 month) treatment discontinued 3 months before enrollment, and (3) suboptimum glucose control (HbA1c between 7.0% and 10.0%, FPG 111 mmol/L, and BMI 1930 kg/m 2 )