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Croatian researcher Predrag Sikiric and colleagues at the University of Zagreb have published the bulk of the animal research over roughly three decades, with studies covering tendon healing, gastric ulceration, colitis, brain injury, and systemic organ protection in rodent models

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Analysis of over 11,000 participants in the SUSTAIN and PIONEER trials revealed that gastrointestinal disorders were the predominant adverse effects, occurring in approximately 39-42% of semaglutide users compared to 22-25% of those receiving comparators

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The most important editorial distinction is between a biological observation in an experimental model and an established outcome in people