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Interestingly, it has been reported that SFN inhibited the activation of NLRP1, NLRP3, and NLRC4 inflammasomes [66,67]

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The mRNA levels of inflammasome-related cytokines, such as Il-1, Il33, Nlrp3 and Myd88 were also increased in the kidneys 7 days after surgery (Fig

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Rather than targeting a single pathway, this peptide combination activates multiple interconnected signaling networks across incretin and amylin receptor systems that collectively enhance metabolic responses beyond what individual components might achieve alone