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When combined with antihypertensive or diuretic agents, the risk of hypokalemia is increased ( FIGURE 5 In addition to blood pressure elevation mediated through renal mechanisms, glycyrrhizin also acts directly on the cardiovascular system in multiple ways

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CMS has the authority to run demonstrations without congressional action, but making obesity drug coverage permanent in Medicare would require Congress to amend the Part D statute to remove the weight-loss exclusion