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These challenges necessitate frequent dosing or the use of modified analogs and innovative delivery systems to sustain therapeutic concentrations

But when theyre off-key, even small changes can affect your weight, energy, and mood

Heidenreich et al., 2022

Psychological stress The emotional side of big body changes (and health anxiety about new medication) can add an extra trigger

Whereas GLP-1 decreases plasma glucose levels by exerting insulinotropic effects, glucagon stimulates hyperglycemia by enhancing hepatic glucose output