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Dermatologists must confirm patients in the iPLEDGE system each month before prescribing the medication, attesting that they have consulted with the patient regarding their Accutane treatment and that they are in possession of a negative pregnancy test if the patient is able to become pregnant

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Unlike the DAC-conjugated version, the no-DAC form lacks the albumin-binding linker and is studied as a short-acting GRF analog

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Neuropharmacology 229 , 109477 (2023)