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Silencing CHAC1 in TRIB3-deficient cells restores GSH levels and reduces arsenite-induced cell death, highlighting the critical role of the TRIB3/CHAC1 axis in regulating cell survival under arsenite stress (Figure 2) (rd et al., 2016)

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And the data collection tools used in trials, like standardized questionnaires and adverse event checklists, may not capture the full range of how patients describe what they are feeling

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