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As your body becomes more efficient at accessing fat stores for fuel, energy availability becomes less dependent on recent food intake

One in ten British adults used or interested in GLP-1 medications for weight loss owenhaskins Jan 8 4 min read In 2025, approximately 4.9 million British adults almost one in ten are estimated to have recently used, or expressed interest in using, glucagon-like peptide-1 (GLP-1) or dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist medications to support weight loss

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Without treatment, it worsens

Third, caloric restriction during intensive weight management further shifts bile acid metabolism