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Generalizing these findings to healthy adults requires significant caution

In addition, despite addressing the degradation on production, the peptide component of this IL17A/IL-22 fusion was still prone to cleavage after in vivo administration 31

However, due to the space-occupying nature of IGB, the stomach walls are unable to fully relax, which may be the mechanism by which IGB patients report symptoms of nausea and vomiting