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The Sanyal Phase 2a in MASLD examined 98 adults with metabolic dysfunction-associated steatotic liver disease and 10 percent liver fat content, randomised to retatrutide or placebo over 48 weeks

These metabolic axes take part in shaping the ferroptosis-susceptible cell-state collectively, and the relative contribution of each axis is likely dictated by the cellular contexts and by the specific ferroptosis-inducing approaches (Fig

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