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By year 2, headache rates were identical in both groups, indicating that the medication-related excess seen in shorter trials doesnt persist long term

NF-B is identified as a transcription factor with a pivotal role in managing inflammation and immune responses, as well as in the transcriptional control of various chemokines and cytokines

Dose titration following the recommended schedule helps minimise side effects whilst allowing physiological adaptation to the medication's effects

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