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This was true of the antiinflammatory medication Vioxx, which was discovered to increase the risk of heart attacks in men over 50 only after it was in widespread use
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Neurons co-expressing orexigenic neuropeptide Y (NYP) and agouti-related peptide (AgRP) in the ARH activate melanocortin hormone- and orexin-expressing neurons in the lateral thalamus, leading to increase food intake
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