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The significant difference in activity between the flavonoids tested in the DPPH assay can be understood by examining their molecular structures

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and trial design factors (endpoint selection, follow-up length)

Am J Physiol Lung Cell Mol Physiol 322(1):L64L83 Dinardo G, del Giudice MM, Drago L, Daglia M, Gori A, Varricchio A, Miraglia del Giudice M, Trincianti C, Tondina E, Brunese FP, Brindisi G, Naso M, Zicari AM, Ciprandi G, Indolfi C (2024) A review of clinical and preclinical data supporting a role for resveratrol in the treatment of common respiratory tract pathogens