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Integrative Medicine: A Clinician's Journal, 14 (4), 35-48

Clinical and experimental studies determine significant reductions in markers of gastrointestinal inflammation, such as CRP and TNF-, following IF interventions, suggesting its role in attenuating systemic and local inflammation [82, 83]

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The dose of berberine commonly used in randomized controlled trials is 300-500mg 3x per day

If you are a strict vegetarian or vegan, its important to eat breads, cereals, or other grains that have been fortified with vitamin B12, or take a daily supplement