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However, intravenous infusion of OXA in humans does not appear to induce any hunger-stimulating drive but increases gastric emptying (35)

In studies on cardiovascular diseases, GLP-1RAs have shown potential benefits

11-13 GLP-1 receptors are expressed in multiple tissues, therefore, GLP-1RAs have multiple mechanisms of action (Figure 2)

"People think constipation is just constipation, but that constipation can turn into intestinal obstruction that can cause perforation and people can die," says Kessler