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Cyproterone acetate Cyproterone acetate is a progesterone derivative that prevents dihydroxytestosterone from binding to the androgen receptor and inhibits release of follicle-stimulating hormone and luteinizing hormone, thereby reducing testosterone levels

We do not know what fraction reaches systemic circulation in humans, and "detectable GI effect" does not equal "adequate systemic bioavailability for joint repair." The acetate salt versus free acid labeling problem

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