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b , Top 5 enriched functional terms for the 1501 differentially expressed genes that were upregulated following GLP-1MK-801 treatment

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Common signs and symptoms of PCOS due to the above etiologies: Acne Irregular menstrual cycle Anovulatory cycles Abnormal mid cycle bleeding Amenorrhea Excessive or heavy bleeding Alopecia (balding) Hirsutism (excessive body hair) Acanthosis nigricans (hyperpigmentation of the skin) Obesity History of recurrent miscarriages Infertility This condition arises when ovulation does not occur regularly, resulting in multiple cysts in the ovary

Native human amylin has limitations for treatment use