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It is important to distinguish between injection-site bruising and more widespread or unexplained bruising, which may indicate an underlying haematological disorder or interaction with anticoagulant or antiplatelet medications

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For electrophysiology and immunohistochemistry experiments, Pomc -humanized Renilla reniformis green fluorescent protein (hrGFP) mice (#006421, Jackson Laboratory, Bar Harbor, ME, USA) were utilized

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