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In the diabetes group, patients on semaglutide had a fourfold increased risk of NAION compared to those on other treatments

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Furthermore, challenges such as low drug concentration at the local pathological site after systemic administration, limited target specificity and short drug half-life persist [6]

Variants such as GLP1R rs6923761 and FTO rs9939609 relate to GLP-1 receptor sensitivity and metabolic regulationfactors that may have additional relevance for post-thyroidectomy patients whose baseline metabolism is already altered

When gut microbiome composition shifts, it can reduce the protective bacterial populations that serve as the first line of defense against urinary pathogens