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B12 Injection Candidates There are a number of reasons that a B12 deficiency might occur

Severe Health Risks Acromegaly-like Effects: Similar to Growth Hormone (GH) abuse, IGF-1 LR3 abuse can lead to acromegaly, a long-term condition in which body tissues get larger over time

doi: 10.1038/s41580-020-00313-x

Too little and you're wasting money

In the case of thin, crepey skin with many small wrinkles, the skin lacks its youthful support of collagen - and that can be corrected with collagen-induction therapies (there are non-invasive, non-surgical, and surgical options - generally speaking there is a trade-off between less invasive procedures needing more treatment sessions to achieve the same result as a more invasive procedure within this category of treatment)