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Good LM, Miller MD, High WA

This metabolic shift is separate from any direct drug effect on thyroid tissue and reflects your body's natural adjustment to a lower weight

Thats potentially quite alarming

The detoxification of xenobiotics and excretion of hydrophilic metabolites is brought about by an initial oxidative step that utilises ROS, followed by conjugation of the intermediate metabolite with glucuronic acid, inorganic sulphur, acetyl groups or GSH via GSH transferases (GST) (70, 154)