Notably, rodents have only the first four GPx isoenzymes (GPx1-GPx4) as the selenoenzymes and the remaining four (GPx4-GPx8) as the cysteine-containing enzymes [1, 8, 9]
There may be nausea and vomiting in 3% of the patients
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Moreover, saffron treatment significantly upregulated the mRNA expression and activity of antioxidant enzymes (SOD, GPx, and CAT), increased Bcl-2 expression, and downregulated Bax expression
