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Thus, we recommend to regularly assess cognitive function among PwPD, test Vit B12 serum levels along with Hcy and MMA levels

2.7 Immunocytochemistry: preparation of Alexa Fluor-labeled proteins, cell surface binding, endocytosis, and downregulation of TfRs HemeHPX in PBS was fluorescently labeled using Alexa Fluor (AF) 546 or 647, according to the manufacturers instructions (Invitrogen)

This reduction in heat-generating capacity and insulation leads to increased cold sensitivity, particularly in the extremities

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