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However, the herein gathered results from bulk RNA-sequencing analyses and functional assays in different 2D and 3D test systems cannot conclusively explain the mechanism underlying the anti-inflammatory and anti-fibrotic effects of aloxistatin

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Specialized nanosystems have shown unique advantages in addressing neurological diseases due to their ability to overcome the BBB, the major obstacle for delivery of therapeutic agents into the brain

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There have also been rare reports of kidney infarction and other severe reactions