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Zhang Y, Brady M, Smith S

When the maintenance dose exceeds roughly 60 units of draw volume, most protocols either switch to a more concentrated reconstitution (10 mg vial in 1.5 mL gives 6.67 mg/mL, so 2.4 mg is just 36 units) or split the weekly dose into two smaller injections to keep individual draws comfortably under 50 units

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The medication promotes natriuresis, the excretion of sodium through the urine, which helps to reduce fluid volume and subsequently lower blood pressure