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Fmoc-Ser(GlcNAc(Ac)3-β-D)-OH
Sialyl Tn (Neu5Acα2-6GalNAcα-O-Thr) at position Thr53
The terminal amine is protected with a benzyloxycarbonyl (Cbz) group
producing high-avidity binding that substantially exceeds the affinity of monovalent GalNAc ligands and closely mimics the geometry of clinically validated Tri-GalNAc targeting moieties used in approved GalNAc-siRNA therapeutics
N-α-Fmoc-O-β-(2-acetamido-3
ES911020: 4-Nitrophenyl 6-O-α-D-Glucopyranosyl-α-D-Glucopyranoside Pack Size:25 mg Fmoc-Ser(GlcNAc(Ac)3-β-D)-OHC18H25NO13 463. 39 A 4 nitrophenyl glycoside of isomaltose (Glc1 6Glc), an 1 6 linked glucose disaccharide. Used as a chromogenic substrate for glucosidases and isomaltases with 1 6 linkage selectivity (e. g., sucrase isomaltase, oligo 1,6 glucosidase, and other debranching glucosidases); enzymatic cleavage of the aglycone proximal glucosidic bond releases 4 nitrophenol. 4 Nitrophenyl (pNP) glycosides are chromogenic enzyme substrates: cleavage of the
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